Co-Enzyme Q10 plays a major role in ATP(energy) production, so its not surprising at all that deficiencies and low levels of this nutrient can cause chronic fatigue and many other symptoms.
Many experts such as Dr Sarah Myhill believe that mitochondrial dysfunction to be the central cause of chronic fatigue syndrome and i would definitely agree with their hypothesis after my own personal battle with CFS.
Some nutrients that are worth testing for include co-enzyme Q10, red blood cell magnesium, zinc, copper, l-carnitine and alpha lipoic acid, which can be tested for using spectralcell intracellular micronutrient testing.
Personally after years of crippling exhaustion, chronic fatigue, shortness of breath, poor exercise tolerance and a myriad of other symptoms, i decided it was time to get my co-enzyme q10 levels checked.
Not surprisingly my test came back that i was SEVERELY deficient in Co-Enzyme Q10.
My test results below from Medi Checks. (Click to view full-size image).
Prior to having done these sort of tests, i was just being constantly fobbed off by doctors that my chronic health problems were just anxiety, depression or even psycho-somatic for around 10+ years. I trialled many anti-depressants such as citalopram and mirtazapine on my doctors orders with no benefit and encountering many side-effects in the process.
Even when i presented my doctor many of the private tests such as the above that i had gone to the point of financially funding myself, my doctor hadn't even heard of Co-Enzyme Q10 before and as such was obviously of no help.
I find it quite embarrasing for a general practitioner to have never heard of a nutrient as important as Co-Enyme Q10. These doctors probably prescribe statin(cholesterol lowering) drugs daily to their patients and as the research has shown statin medications lower levels of Co-Enyme Q10, which induces mitochondrial dysfunction and statins are even proven to cause heart failure. Many of these doctors simply don't have a clue about the drugs they are prescribing half the time.
We rely on these doctors to get us well, but the majority seem to be not only clearly under-educated when it comes to health problems such as CFS/ME, but the majority are also completely not interested in helping you get well.
Im not one for conspiracy theories, but it really does seem to be about prescribing anti-depressants and often pointless therapies such as CBT(Cognitive Behavioral Therapy). Some of the counselling and CBT that i received on the NHS was beyond pathetic, most of these physicians were more interested in fighting with me, rather than helping me get well.
I would love to be able to go back now to these past doctors and psychiatrists to show them the burden of proof that i have built with real tests, which show that my CFS and many other health problems had many bio-chemical under-lying root causes such as impairments in ATP production(co-enzyme q10 deficiency), hpa-axis dysregulation aka "adrenal fatigue" and low cortisol levels, genetic defects such as pyrrole disorder(pyroluria)/disturbed vitamin B6/zinc metabolism, toxic heavy metal overload and many other issues that required being corrected.
When you have chronic health problems such as CFS/ME or any auto-immune disease for that matter, you really have to take your own health into your hands if you want to get well
Id love to ask these doctors how taking anti-depressants or paced exercise was going to rectify this underlying and very important pathophysiology in Co-Enzyme Q10 deficiency.
There is a good study which showed that Co-Enzyme Q10 deficiency in individuals with CFS/ME was related to the fatigue, autonomic and neuro-cognitive symptoms that these people suffer from.
Not only that, but the study found that Co-Enzyme Q10 deficiency was another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder.
Which in my opinions just goes to show how important a role Co-Enzyme Q10 deficiency plays in the pathophysiology of chronic fatigue syndrome/ME.
Like many other studies, the research found that Co-Enzyme Q10 levels were once again significantly lower in those with CFS/ME and that there was a significant and inverse relationship between Co-Q10 levels and the severity of the symptoms such as fatigue, concentration and memory disturbances.
The study below is well worth a read for any individual diagnosed with ME/CFS, as is getting your Co-Enzyme Q10 levels tested for.
1. Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder.